387 research outputs found
Influence of Alternaria spp. on susceptibility of canola and mustard to Pythium spp., Fusarium spp., and Rhizoctonia solani
Non-Peer ReviewedSeed exudates have been shown to inhibit the growth of some fungi responsible for seed
rot and seedling blight in canola and mustard. Alternaria brassicae, A. alternata and A.
raphani can all be found on seed of canola and mustard. Previous work indicates deep
infections of Alternaria brassicae and A. raphani significantly reduce seed germination
while A. alternata had no direct effect on germination. The objective of this study is to
determine the effect of seed exudates on seed rot and seedling blight caused by
Rhizoctonia solani, Fusarium spp. and Pythium spp. and determine if seed borne
Alternaria is synergistic to these pathogens by breaking down defensive compounds in
the seed exudates. Seed will be inoculated with Alternaria alternata. to create superficial
surface infection. Susceptibility to Pythium, Fusarium and Rhizoctonia of artificially
infected seed lots and naturally infected seed lots will be tested on water agar, blotter test
and pot test. Seed exudates will also be obtained from seed lots after surface sterilization
and bioassays of the ability of these exudates to support growth of pathogenic fungi and
beneficial bacteria will be assessed
Crossover and scaling in a nearly antiferromagnetic Fermi liquid in two dimensions
We consider two-dimensional Fermi liquids in the vicinity of a quantum
transition to a phase with commensurate, antiferromagnetic long-range order.
Depending upon the Fermi surface topology, mean-field spin-density-wave theory
predicts two different types of such transitions, with mean-field dynamic
critical exponents (when the Fermi surface does not cross the magnetic
zone boundary, type ) and (when the Fermi surface crosses the magnetic
zone boundary, type ). The type system only displays behavior at
all energies and its scaling properties are similar (though not identical) to
those of an insulating Heisenberg antiferromagnet. Under suitable conditions
precisely stated in this paper, the type system displays a crossover from
relaxational behavior at low energies to type behavior at high energies. A
scaling hypothesis is proposed to describe this crossover: we postulate a
universal scaling function which determines the entire, temperature-,
wavevector-, and frequency-dependent, dynamic, staggered spin susceptibility in
terms of 4 measurable, , parameters (determining the distance, energy, and
order parameter scales, plus one crossover parameter). The scaling function
contains the full scaling behavior in all regimes for both type and
systems. The crossover behavior of the uniform susceptibility and the specific
heat is somewhat more complicated and is also discussed. Explicit computation
of the crossover functions is carried out in a large expansion on a
mean-field model. Some new results for the critical properties on the ordered
side of the transition are also obtained in a spin-density wave formalism. The
possible relevance of our results to the doped cuprate compounds is briefly
discussed.Comment: 20 pages, REVTeX, 6 figures (uuencoded compressed PostScript file for
figures is appended
Non-Equilibrium Statistical Physics of Currents in Queuing Networks
We consider a stable open queuing network as a steady non-equilibrium system
of interacting particles. The network is completely specified by its underlying
graphical structure, type of interaction at each node, and the Markovian
transition rates between nodes. For such systems, we ask the question ``What is
the most likely way for large currents to accumulate over time in a network
?'', where time is large compared to the system correlation time scale. We
identify two interesting regimes. In the first regime, in which the
accumulation of currents over time exceeds the expected value by a small to
moderate amount (moderate large deviation), we find that the large-deviation
distribution of currents is universal (independent of the interaction details),
and there is no long-time and averaged over time accumulation of particles
(condensation) at any nodes. In the second regime, in which the accumulation of
currents over time exceeds the expected value by a large amount (severe large
deviation), we find that the large-deviation current distribution is sensitive
to interaction details, and there is a long-time accumulation of particles
(condensation) at some nodes. The transition between the two regimes can be
described as a dynamical second order phase transition. We illustrate these
ideas using the simple, yet non-trivial, example of a single node with
feedback.Comment: 26 pages, 5 figure
Conceptual Model Interoperability: a Metamodel-driven Approach
Linking, integrating, or converting conceptual data models represented in different modelling languages is a common aspect in the design and maintenance of complex information systems. While such languages seem similar, they are known to be distinct and no unifying framework exists that respects all of their language features in either model transformations or inter-model assertions to relate them. We aim to address this issue using an approach where the rules are enhanced with a logic-based metamodel. We present the main approach and some essential metamodel-driven rules for the static, structural, components of ER, EER, UML v2.4.1, ORM, and ORM2. The transformations for model elements and patterns are used with the metamodel to verify correctness of inter-model assertions across models in different languages
Ten millennia of hepatitis B virus evolution
Hepatitis B virus (HBV) has been infecting humans for millennia and remains a global health problem, but its past diversity and dispersal routes are largely unknown. We generated HBV genomic data from 137 Eurasians and Native Americans dated between ~10,500 and ~400 years ago. We date the most recent common ancestor of all HBV lineages to between ~20,000 and 12,000 years ago, with the virus present in European and South American hunter-gatherers during the early Holocene. After the European Neolithic transition, Mesolithic HBV strains were replaced by a lineage likely disseminated by early farmers that prevailed throughout western Eurasia for ~4000 years, declining around the end of the 2nd millennium BCE. The only remnant of this prehistoric HBV diversity is the rare genotype G, which appears to have reemerged during the HIV pandemic
Towards optimal use of antithrombotic therapy of people with cancer at the end of life: a research protocol for the development and implementation of the SERENITY shared decision support tool Thrombosis Research
Background: Even though antithrombotic therapy has probably little or even negative effects on the well-being of people with cancer during their last year of life, deprescribing antithrombotic therapy at the end of life is rare in practice. It is often continued until death, possibly resulting in excess bleeding, an increased disease burden and higher healthcare costs. Methods: The SERENITY consortium comprises researchers and clinicians from eight European countries with specialties in different clinical fields, epidemiology and psychology. SERENITY will use a comprehensive approach combining a realist review, flash mob research, epidemiological studies, and qualitative interviews. The results of these studies will be used in a Delphi process to reach a consensus on the optimal design of the shared decision support tool. Next, the shared decision support tool will be tested in a randomised controlled trial. A targeted implementation and dissemination plan will be developed to enable the use of the SERENITY tool across Europe, as well as its incorporation in clinical guidelines and policies. The entire project is funded by Horizon Europe.Results: SERENITY will develop an information-driven shared decision support tool that will facilitate treatment decisions regarding the appropriate use of antithrombotic therapy in people with cancer at the end of life. Conclusions: We aim to develop an intervention that guides the appropriate use of antithrombotic therapy, prevents bleeding complications, and saves healthcare costs. Hopefully, usage of the tool leads to enhanced empowerment and improved quality of life and treatment satisfaction of people with advanced cancer and their care givers
Projected WIMP sensitivity of the LUX-ZEPLIN dark matter experiment
LUX-ZEPLIN (LZ) is a next-generation dark matter direct detection experiment that will operate 4850 feet underground at the Sanford Underground Research Facility (SURF) in Lead, South Dakota, USA. Using a two-phase xenon detector with an active mass of 7 tonnes, LZ will search primarily for low-energy interactions with weakly interacting massive particles (WIMPs), which are hypothesized to make up the dark matter in our galactic halo. In this paper, the projected WIMP sensitivity of LZ is presented based on the latest background estimates and simulations of the detector. For a 1000 live day run using a 5.6-tonne fiducial mass, LZ is projected to exclude at 90% confidence level spin-independent WIMP-nucleon cross sections above 1.4 × 10-48cm2 for a 40 GeV/c2 mass WIMP.
Additionally, a 5σ discovery potential is projected, reaching cross sections below the exclusion limits of recent experiments. For spin-dependent WIMP-neutron(-proton) scattering, a sensitivity of 2.3 × 10−43 cm2 (7.1 × 10−42 cm2) for a 40 GeV/c2
mass WIMP is expected. With underground installation well underway, LZ is on track for commissioning at SURF in 2020
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